PREPARATION AND IN VITRO/IN VIVO EVALUATION OF PLGA MICROSPHERES CONTAINING NORQUETIAPINE FOR LONG-ACTING INJECTION

Preparation and in vitro/in vivo evaluation of PLGA microspheres containing norquetiapine for long-acting injection

Chun-Woong Park,1 Hyo-Jung Lee,1 Dong-Won Oh,1 Freezer Light Cover Ji-Hyun Kang,1 Chang-Soo Han,1 Dong-Wook Kim21College of Pharmacy, Chungbuk National University, Cheongju, Republic of Korea; 2Department of Pharmaceutical Engineering, Cheongju University, Cheongju, Republic of KoreaBackground: Norquetiapine (N-desalkyl quetiapine, NQ) is an active

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Machine Learning Methods in CFD for Turbomachinery: A Review

Computational Fluid Dynamics is one of the most relied upon tools in the design and analysis of components in turbomachines.From the propulsion fan at the inlet, through the compressor and combustion sections, to the turbines at the outlet, CFD is used to perform fluid flow and heat transfer analyses to help designers extract the highest performanc

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Potent anti-tumor effect generated by a novel human papillomavirus (HPV) antagonist peptide reactivating the pRb/E2F pathway.

Human papillomavirus type 16 (HPV16) E7 is a viral oncoprotein believed to play a major role in cervical cancer.In this study, an antagonist peptide against HPV16E7 protein was first identified from screening the c7c phage display peptide library.The binding specificity and affinity of the selected peptide to HPV16E7 were tested by competitive enzy

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A pilot study to assess compliance and impact of health warnings on tobacco products in the Udupi district of Karnataka State, India

Introduction The Government of India has taken several steps to reduce tobacco use, including legislation in the Cigarettes and Other Tobacco Products Act (COTPA) requiring health warnings on tobacco products.This study assessed compliance with the legislation on warnings, and awareness of these warnings and their perceived impact in preventing tob

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